Structured Summary
Abstract
An E2F transcription factor that interacts directly with RETINOBLASTOMA PROTEIN and CYCLIN A and activates GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F1 is involved in DNA REPAIR and APOPTOSIS.
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Classification
Broader headings
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Synonyms
10 entry terms
- E2F Transcription Factor 1 Protein
- E2F-1 Transcription Factor
- Retinoblastoma Binding Protein 3
- Retinoblastoma-Associated Protein 1
- Transcription Factor E2F-1
- Transcription Factor E2F1
- Retinoblastoma Associated Protein 1
- Transcription Factor E2F 1
- Transcription Factor, E2F-1
- Transcription Factor, E2F1
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
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Indexing Annotation
see SCR for organism-specific terms
MeSH Record
History Note
2006(1991)
MeSH Record
Previous Indexing
- Cell Cycle Proteins (1991-2005)
- DNA-Binding Proteins (1991-2005)
- Transcription Factors (1991-2005)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. E2F1 Transcription Factor. Medical Subject Headings (MeSH). 2026. Unique ID D050687. http://id.nlm.nih.gov/mesh/2026/D050687
- E2F1 Transcription Factor. In: Wikidata. https://www.wikidata.org/wiki/Q5322375