Phenomena and Processes

E-Box Elements

DNA locations with the consensus sequence CANNTG. ENHANCER ELEMENTS may contain multiple copies of this element. E-boxes play a regulatory role in the control of transcription. They bind with basic helix-loop-helix (bHLH) type TRANSCRIPTION FACTORS. Binding specificity is determined by the specific bHLH heterodimer or homodimer combination and by the specific nucleotides at the 3rd and 4th position of the E-box sequence.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

DNA locations with the consensus sequence CANNTG. ENHANCER ELEMENTS may contain multiple copies of this element. E-boxes play a regulatory role in the control of transcription. They bind with basic helix-loop-helix (bHLH) type TRANSCRIPTION FACTORS. Binding specificity is determined by the specific bHLH heterodimer or homodimer combination and by the specific nucleotides at the 3rd and 4th position of the E-box sequence.

MeSH Record

Classification

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MeSH Record

Synonyms

19 entry terms
  • E-Box Motifs
  • E-Box Sequences
  • E-Box Sites
  • E Box Elements
  • E Box Motifs
  • E Box Sequences
  • E Box Sites
  • E-Box Element
  • E-Box Motif
  • E-Box Sequence
  • E-Box Site
  • Element, E-Box
  • Elements, E-Box
  • Motif, E-Box
  • Motifs, E-Box
  • Sequence, E-Box
  • Sequences, E-Box
  • Site, E-Box
  • Sites, E-Box

MeSH Record

Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2002

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. E-Box Elements. Medical Subject Headings (MeSH). 2026. Unique ID D024721. http://id.nlm.nih.gov/mesh/2026/D024721
  2. E-Box Elements. In: Wikipedia. https://en.wikipedia.org/wiki/E-box
  3. E-Box Elements. In: Wikidata. https://www.wikidata.org/wiki/Q3825657