Chemicals and Drugs

Dothiepin

A tricyclic antidepressant with some tranquilizing action.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A tricyclic antidepressant with some tranquilizing action.

Chemical Identity

Chemical Information

Molecular Formula
C19H21NS
Molecular Weight
295.4 g/mol
CAS Registry No.
113-53-1
IUPAC Name
3-(6H-benzo[c][1]benzothiepin-11-ylidene)-N,N-dimethylpropan-1-amine
InChIKey
PHTUQLWOUWZIMZ-UHFFFAOYSA-N
SMILES
CN(C)CCC=C1C2=CC=CC=C2CSC3=CC=CC=C31
MeSH Unique ID
D004308
Source
PubChem CID 3155

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

4 entry terms
  • Dosulepin
  • Dothiepin Hydrochloride
  • Prothiaden
  • Hydrochloride, Dothiepin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(79); was see under DIBENZOTHIEPINS 1979-90; was PROTHIADENE see under DIBENZOTHIEPINS 1968-78; PROTHIADENE was see DOTHIEPIN 1979-94

MeSH Record

Previous Indexing

  • Dibenzothiepins (1968-1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Dothiepin. Medical Subject Headings (MeSH). 2026. Unique ID D004308. http://id.nlm.nih.gov/mesh/2026/D004308
  2. Dothiepin. In: Wikipedia. https://en.wikipedia.org/wiki/Dosulepin
  3. Dothiepin. In: Wikidata. https://www.wikidata.org/wiki/Q27116967
  4. Dothiepin. In: PubChem Compound. CID 3155. https://pubchem.ncbi.nlm.nih.gov/compound/3155