Structured Summary
Abstract
A reagent commonly used in biochemical studies as a protective agent to prevent the oxidation of SH (thiol) groups and for reducing disulphides to dithiols.
Chemical Identity
Chemical Information
- Molecular Formula
- C4H10O2S2
- Molecular Weight
- 154.3 g/mol
- CAS Registry No.
- 27565-41-9
- IUPAC Name
- (2S,3S)-1,4-bis(sulfanyl)butane-2,3-diol
- InChIKey
- VHJLVAABSRFDPM-QWWZWVQMSA-N
- SMILES
- C([C@H]([C@@H](CS)O)O)S
- MeSH Unique ID
- D004229
- Source
- PubChem CID 446094
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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MeSH Record
Synonyms
6 entry terms
- Cleland Reagent
- Cleland's Reagent
- Clelands Reagent
- Reagent, Cleland
- Reagent, Cleland's
- Sputolysin
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
72
MeSH Record
Previous Indexing
- Alcohols (1966-1971)
- Tetroses (1966-1971)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Dithiothreitol. Medical Subject Headings (MeSH). 2026. Unique ID D004229. http://id.nlm.nih.gov/mesh/2026/D004229
- Dithiothreitol. In: Wikipedia. https://en.wikipedia.org/wiki/Dithiothreitol
- Dithiothreitol. In: Wikidata. https://www.wikidata.org/wiki/Q414783
- Dithiothreitol. In: PubChem Compound. CID 446094. https://pubchem.ncbi.nlm.nih.gov/compound/446094