Chemicals and Drugs

Dipyridamole

A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)

Chemical Identity

Chemical Information

Molecular Formula
C24H40N8O4
Molecular Weight
504.6 g/mol
CAS Registry No.
58-32-2
IUPAC Name
2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol
InChIKey
IZEKFCXSFNUWAM-UHFFFAOYSA-N
SMILES
C1CCN(CC1)C2=NC(=NC3=C2N=C(N=C3N4CCCCC4)N(CCO)CCO)N(CCO)CCO
MeSH Unique ID
D004176
Source
PubChem CID 3108

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

14 entry terms
  • Dipyramidole
  • Antistenocardin
  • Apo-Dipyridamole
  • Cerebrovase
  • Cléridium
  • Curantil
  • Curantyl
  • Kurantil
  • Miosen
  • Novo-Dipiradol
  • Persantin
  • Persantine
  • Apo Dipyridamole
  • Novo Dipiradol

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

66; was PERSANTIN 1963-65

MeSH Hierarchy

Tree Number

  1. D03w.383.742.175w

MeSH Record

NLM Classification

QV 150

AMA Style

References

  1. National Library of Medicine. Dipyridamole. Medical Subject Headings (MeSH). 2026. Unique ID D004176. http://id.nlm.nih.gov/mesh/2026/D004176
  2. Dipyridamole. In: Wikipedia. https://en.wikipedia.org/wiki/Dipyridamole
  3. Dipyridamole. In: Wikidata. https://www.wikidata.org/wiki/Q419374
  4. Dipyridamole. In: PubChem Compound. CID 3108. https://pubchem.ncbi.nlm.nih.gov/compound/3108