Chemicals and Drugs

Diltiazem

A benzothiazepine derivative with vasodilating action due to its antagonism of the actions of CALCIUM ion on membrane functions.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A benzothiazepine derivative with vasodilating action due to its antagonism of the actions of CALCIUM ion on membrane functions.

Chemical Identity

Chemical Information

Molecular Formula
C22H26N2O4S
Molecular Weight
414.5 g/mol
CAS Registry No.
42399-41-7
IUPAC Name
[(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate
InChIKey
HSUGRBWQSSZJOP-RTWAWAEBSA-N
SMILES
CC(=O)O[C@@H]1[C@@H](SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC
MeSH Unique ID
D004110
Source
PubChem CID 39186

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

13 entry terms
  • Aldizem
  • CRD-401
  • Cardil
  • Cardizem
  • Dilacor
  • Dilacor XR
  • Dilren
  • Diltiazem Hydrochloride
  • Diltiazem Malate
  • Dilzem
  • Tiazac
  • CRD 401
  • CRD401

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

87(79); was see under BENZAZEPINES 1979-86; was CRD 401 see under BENZAZEPINES 1975-78

MeSH Record

Previous Indexing

  • Anisoles (1973-1974)
  • Benzazepines (1971-1974)
  • Dimethylamines (1973-1974)

MeSH Hierarchy

Tree Number

MeSH Record

NLM Classification

QV 150

AMA Style

References

  1. National Library of Medicine. Diltiazem. Medical Subject Headings (MeSH). 2026. Unique ID D004110. http://id.nlm.nih.gov/mesh/2026/D004110
  2. Diltiazem. In: Wikipedia. https://en.wikipedia.org/wiki/Diltiazem
  3. Diltiazem. In: Wikidata. https://www.wikidata.org/wiki/Q422229
  4. Diltiazem. In: PubChem Compound. CID 39186. https://pubchem.ncbi.nlm.nih.gov/compound/39186