Chemicals and Drugs

Dihydroxyphenylalanine

A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.

MeSH Record

Classification

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

See Also

MeSH Record

Synonyms

8 entry terms
  • 3,4-Dihydroxyphenylalanine
  • 3-Hydroxy-DL-tyrosine
  • Dopa
  • beta-Hydroxytyrosine
  • 3 Hydroxy DL tyrosine
  • 3,4 Dihydroxyphenylalanine
  • beta Hydroxytyrosine
  • Dihydroxyphenylalanine Hydrochloride, (2:1)

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

check text to see if LEVODOPA; (L-DOPA); is not meant instead

MeSH Record

History Note

2002(1966); for BETA-HYDROXYTYROSINE use DIHYDOXYPHENYLALANINE (NM) 1989-1991

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

WK 725

AMA Style

References

  1. National Library of Medicine. Dihydroxyphenylalanine. Medical Subject Headings (MeSH). 2026. Unique ID D004295. http://id.nlm.nih.gov/mesh/2026/D004295
  2. Dihydroxyphenylalanine. In: Wikidata. https://www.wikidata.org/wiki/Q27121510