Chemicals and Drugs

Dihydrouracil Dehydrogenase (NADP)

An oxidoreductase involved in pyrimidine base degradation. It catalyzes the catabolism of THYMINE; URACIL and the chemotherapeutic drug, 5-FLUOROURACIL.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An oxidoreductase involved in pyrimidine base degradation. It catalyzes the catabolism of THYMINE; URACIL and the chemotherapeutic drug, 5-FLUOROURACIL.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

4 entry terms
  • DPYD Protein
  • Dihydropyrimidine Dehydrogenase
  • Dihydrothymine Dehydrogenase (NADP)
  • Dehydrogenase, Dihydropyrimidine

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2004; use DIHYDROURACIL DEHYDROGENASE (NADP) (NM) 1980-2003

MeSH Record

Previous Indexing

  • Oxidoreductases (1980-2003)
  • Uracil (1979)

MeSH Hierarchy

Tree Number

  1. D08.811w.682w.660.350w

AMA Style

References

  1. National Library of Medicine. Dihydrouracil Dehydrogenase (NADP). Medical Subject Headings (MeSH). 2026. Unique ID D042943. http://id.nlm.nih.gov/mesh/2026/D042943
  2. Dihydrouracil Dehydrogenase (NADP). In: Wikipedia. https://en.wikipedia.org/wiki/Dihydropyrimidine_dehydrogenase_(NADP%2B)
  3. Dihydrouracil Dehydrogenase (NADP). In: Wikidata. https://www.wikidata.org/wiki/Q1114455