Chemicals and Drugs

Dihydrolipoyllysine-Residue Acetyltransferase

An enzyme that catalyzes the acetyltransferase reaction using ACETYL CoA as an acetyl donor and dihydrolipoamide as acceptor to produce COENZYME A (CoA) and S-acetyldihydrolipoamide. It forms the (E2) subunit of the PYRUVATE DEHYDROGENASE COMPLEX.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that catalyzes the acetyltransferase reaction using ACETYL CoA as an acetyl donor and dihydrolipoamide as acceptor to produce COENZYME A (CoA) and S-acetyldihydrolipoamide. It forms the (E2) subunit of the PYRUVATE DEHYDROGENASE COMPLEX.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

17 entry terms
  • Acetyl-CoA-Dihydrolipoamide S-Acetyltransferase
  • Dihydrolipoamide Acetyltransferase
  • Dihydrolipoamide S-Acetyltransferase
  • Dihydrolipoyl Acetyltransferase
  • Dihydrolipoyl Transacetylase
  • Lipoate Acetyltransferase
  • Pyruvate Dehydrogenase Complex E2
  • Acetyl CoA Dihydrolipoamide S Acetyltransferase
  • Acetyltransferase, Dihydrolipoamide
  • Acetyltransferase, Dihydrolipoyl
  • Acetyltransferase, Dihydrolipoyllysine-Residue
  • Acetyltransferase, Lipoate
  • Dihydrolipoamide S Acetyltransferase
  • Dihydrolipoyllysine Residue Acetyltransferase
  • S-Acetyltransferase, Acetyl-CoA-Dihydrolipoamide
  • S-Acetyltransferase, Dihydrolipoamide
  • Transacetylase, Dihydrolipoyl

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1980); use PYRUVATE DEHYDROGENASE COMPLEX, ACETYLTRANSFERASES & under LIPOIC ACID 1968-1979

MeSH Hierarchy

Tree Numbers

  1. D05.500w.562w.625w.750
  2. D08.811w.600w.741w.625
  3. D08.811w.913w.050w.134w.310

AMA Style

References

  1. National Library of Medicine. Dihydrolipoyllysine-Residue Acetyltransferase. Medical Subject Headings (MeSH). 2026. Unique ID D051047. http://id.nlm.nih.gov/mesh/2026/D051047
  2. Dihydrolipoyllysine-Residue Acetyltransferase. In: Wikidata. https://www.wikidata.org/wiki/Q76725512