Structured Summary
Abstract
A 9,10alpha-dihydro derivative of ERGOTAMINE. It is used as a vasoconstrictor, specifically for the therapy of MIGRAINE DISORDERS.
Chemical Identity
Chemical Information
- Molecular Formula
- C33H37N5O5
- Molecular Weight
- 583.7 g/mol
- CAS Registry No.
- 511-12-6
- IUPAC Name
- (6aR,9R,10aR)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
- InChIKey
- LUZRJRNZXALNLM-JGRZULCMSA-N
- SMILES
- C[C@@]1(C(=O)N2[C@H](C(=O)N3CCC[C@H]3[C@@]2(O1)O)CC4=CC=CC=C4)NC(=O)[C@@H]5C[C@H]6[C@@H](CC7=CNC8=CC=CC6=C78)N(C5)C
- MeSH Unique ID
- D004087
- Source
- PubChem CID 10531
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
Drug Class
Pharmacological Action
MeSH Record
Synonyms
34 entry terms
- Agit
- Angionorm
- Clavigrenin
- D-Tamin Retard L.U.T.
- D.H.E. 45
- DET MS
- DHE-45
- DHE-Puren
- DHE-Ratiopharm
- Dihydergot
- Dihydroergotamin AL
- Dihydroergotamine Mesylate
- Dihydroergotamine Methanesulfonate
- Dihydroergotamine-Sandoz
- Dihytamin
- Erganton
- Ergomimet
- Ergont
- Ergotam Von Ct
- Ikaran
- Migranal
- Orstanorm
- Seglor
- Tamik
- Verladyn
- D Tamin Retard L.U.T.
- DHE 45
- DHE Puren
- DHE Ratiopharm
- DHE45
- Dihydroergotamine Sandoz
- Mesylate, Dihydroergotamine
- Methanesulfonate, Dihydroergotamine
- Von Ct, Ergotam
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
78(75); was see under ERGOTAMINE 1963-77
MeSH Record
Previous Indexing
- Ergotamine (1966-1974)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Dihydroergotamine. Medical Subject Headings (MeSH). 2026. Unique ID D004087. http://id.nlm.nih.gov/mesh/2026/D004087
- Dihydroergotamine. In: Wikipedia. https://en.wikipedia.org/wiki/Dihydroergotamine
- Dihydroergotamine. In: Wikidata. https://www.wikidata.org/wiki/Q421336
- Dihydroergotamine. In: PubChem Compound. CID 10531. https://pubchem.ncbi.nlm.nih.gov/compound/10531