Chemicals and Drugs

Diethylstilbestrol

A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed)

Chemical Identity

Chemical Information

Molecular Formula
C18H20O2
Molecular Weight
268.3 g/mol
CAS Registry No.
56-53-1
IUPAC Name
4-[(E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol
InChIKey
RGLYKWWBQGJZGM-ISLYRVAYSA-N
SMILES
CC/C(=C(/CC)\C1=CC=C(C=C1)O)/C2=CC=C(C=C2)O
MeSH Unique ID
D004054
Source
PubChem CID 448537

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

9 entry terms
  • Stilbene Estrogen
  • Estrogen, Stilbene
  • Agostilben
  • Apstil
  • Diethylstilbestrol, (Z)-Isomer
  • Diethylstilbestrol, Disodium Salt
  • Distilbène
  • Stilbestrol
  • Tampovagan

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Number

  1. D02w.455w.426w.559w.389.150w.700w.725.500w

MeSH Record

NLM Classification

WP 522

AMA Style

References

  1. National Library of Medicine. Diethylstilbestrol. Medical Subject Headings (MeSH). 2026. Unique ID D004054. http://id.nlm.nih.gov/mesh/2026/D004054
  2. Diethylstilbestrol. In: Wikipedia. https://en.wikipedia.org/wiki/Diethylstilbestrol
  3. Diethylstilbestrol. In: Wikidata. https://www.wikidata.org/wiki/Q423989
  4. Diethylstilbestrol. In: PubChem Compound. CID 448537. https://pubchem.ncbi.nlm.nih.gov/compound/448537