Chemicals and Drugs

Dienestrol

A synthetic, non-steroidal estrogen structurally related to stilbestrol. It is used, usually as the cream, in the treatment of menopausal and postmenopausal symptoms.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A synthetic, non-steroidal estrogen structurally related to stilbestrol. It is used, usually as the cream, in the treatment of menopausal and postmenopausal symptoms.

Chemical Identity

Chemical Information

Molecular Formula
C18H18O2
Molecular Weight
266.3 g/mol
CAS Registry No.
84-17-3
IUPAC Name
4-[(2E,4E)-4-(4-hydroxyphenyl)hexa-2,4-dien-3-yl]phenol
InChIKey
NFDFQCUYFHCNBW-SCGPFSFSSA-N
SMILES
C/C=C(/C(=C/C)/C1=CC=C(C=C1)O)\C2=CC=C(C=C2)O
MeSH Unique ID
D004028
Source
PubChem CID 667476

MeSH Record

Classification

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • 4,4'-(Diethylideneethylene)diphenol
  • Dienoestrol
  • Dienestrol, (E,E)-Isomer
  • Dienestrol, (Z,E)-Isomer
  • Dienestrol, (Z,Z)-Isomer
  • Oestrasid
  • Ortho Dienestrol
  • Synestrol

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under PHENOLS 1975-90

MeSH Record

Previous Indexing

  • Alkadienes (1974)
  • Phenols (1969-1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Dienestrol. Medical Subject Headings (MeSH). 2026. Unique ID D004028. http://id.nlm.nih.gov/mesh/2026/D004028
  2. Dienestrol. In: Wikipedia. https://en.wikipedia.org/wiki/(E,E)-dienestrol
  3. Dienestrol. In: Wikidata. https://www.wikidata.org/wiki/Q5274949
  4. Dienestrol. In: PubChem Compound. CID 667476. https://pubchem.ncbi.nlm.nih.gov/compound/667476