Chemicals and Drugs

Diazepam

A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.

Chemical Identity

Chemical Information

Molecular Formula
C16H13ClN2O
Molecular Weight
284.74 g/mol
CAS Registry No.
439-14-5
IUPAC Name
7-chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2-one
InChIKey
AAOVKJBEBIDNHE-UHFFFAOYSA-N
SMILES
CN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3
MeSH Unique ID
D003975
Source
PubChem CID 3016

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

See Also

MeSH Record

Synonyms

9 entry terms
  • 7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one
  • Apaurin
  • Diazemuls
  • Faustan
  • Relanium
  • Seduxen
  • Sibazon
  • Stesolid
  • Valium

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

65(63)

MeSH Hierarchy

Tree Number

  1. D03w.633.100.079.080w.070.216w

MeSH Record

NLM Classification

QV 77.9

AMA Style

References

  1. National Library of Medicine. Diazepam. Medical Subject Headings (MeSH). 2026. Unique ID D003975. http://id.nlm.nih.gov/mesh/2026/D003975
  2. Diazepam. In: Wikipedia. https://en.wikipedia.org/wiki/Diazepam
  3. Diazepam. In: Wikidata. https://www.wikidata.org/wiki/Q210402
  4. Diazepam. In: PubChem Compound. CID 3016. https://pubchem.ncbi.nlm.nih.gov/compound/3016