Chemicals and Drugs

Dextrorphan

Dextro form of levorphanol. It acts as a noncompetitive NMDA receptor antagonist, among other effects, and has been proposed as a neuroprotective agent. It is also a metabolite of DEXTROMETHORPHAN.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Dextro form of levorphanol. It acts as a noncompetitive NMDA receptor antagonist, among other effects, and has been proposed as a neuroprotective agent. It is also a metabolite of DEXTROMETHORPHAN.

Chemical Identity

Chemical Information

Molecular Formula
C17H23NO
Molecular Weight
257.37 g/mol
CAS Registry No.
125-73-5
IUPAC Name
(1S,9S,10S)-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol
InChIKey
JAQUASYNZVUNQP-PVAVHDDUSA-N
SMILES
CN1CC[C@@]23CCCC[C@@H]2[C@@H]1CC4=C3C=C(C=C4)O
MeSH Unique ID
D003917
Source
PubChem CID 5360697

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

1 entry terms
  • (+-)-17-Methylmorphinan-3-ol

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under MORPHINANS 1975-90; DEXTRODROMORAN & D-DROMORAN were see DEXTRORPHAN 1977-94; DESTRORPHANOLUM was see DEXTRORPHAN 1975-94

MeSH Record

Previous Indexing

  • Morphinans (1969-1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Dextrorphan. Medical Subject Headings (MeSH). 2026. Unique ID D003917. http://id.nlm.nih.gov/mesh/2026/D003917
  2. Dextrorphan. In: Wikipedia. https://en.wikipedia.org/wiki/Dextrorphan
  3. Dextrorphan. In: Wikidata. https://www.wikidata.org/wiki/Q659468
  4. Dextrorphan. In: PubChem Compound. CID 5360697. https://pubchem.ncbi.nlm.nih.gov/compound/5360697