Chemicals and Drugs

Dexamethasone Isonicotinate

An anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, locally, and parenterally. It may cause water and salt retention.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, locally, and parenterally. It may cause water and salt retention.

Chemical Identity

Chemical Information

Molecular Formula
C28H32FNO6
Molecular Weight
497.6 g/mol
CAS Registry No.
2265-64-7
IUPAC Name
[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] pyridine-4-carboxylate
InChIKey
BQTXJHAJMDGOFI-NJLPOHDGSA-N
SMILES
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)COC(=O)C5=CC=NC=C5)O)C)O)F)C
MeSH Unique ID
D003908
Source
PubChem CID 16752

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

5 entry terms
  • Isonicotinate, Dexamethasone
  • Auxison
  • HE-111
  • HE 111
  • HE111

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(76); was see under DEXAMETHASONE 1976-90

MeSH Record

Previous Indexing

  • Dexamethasone (1972-1974) /analogs & derivatives (1975)
  • Isonicotinic Acids (1972-1975)

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.745.432w.769.344w.300w
  2. D04w.210.500w.908.238w.300w

AMA Style

References

  1. National Library of Medicine. Dexamethasone Isonicotinate. Medical Subject Headings (MeSH). 2026. Unique ID D003908. http://id.nlm.nih.gov/mesh/2026/D003908
  2. Dexamethasone Isonicotinate. In: Wikipedia. https://en.wikipedia.org/wiki/Dexamethasone_isonicotinate
  3. Dexamethasone Isonicotinate. In: Wikidata. https://www.wikidata.org/wiki/Q5268313
  4. Dexamethasone Isonicotinate. In: PubChem Compound. CID 16752. https://pubchem.ncbi.nlm.nih.gov/compound/16752