Chemicals and Drugs

Dexamethasone Drug Combination Tobramycin

A topical preparation of tobramycin and dexamethasone that is used for treating or preventing superficial bacterial infections of the eye.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A topical preparation of tobramycin and dexamethasone that is used for treating or preventing superficial bacterial infections of the eye.

Chemical Identity

Chemical Information

Molecular Formula
C40H66FN5O14
Molecular Weight
860.0 g/mol
CAS Registry No.
288392-57-4
IUPAC Name
(2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol;(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
InChIKey
DWLNMMCXGSKYEM-VQHMUFKESA-N
SMILES
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C.C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)N)O)O)O[C@@H]3[C@@H](C[C@@H]([C@H](O3)CN)O)N)N
MeSH Unique ID
D000078162
Source
PubChem CID 11949636

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

5 entry terms
  • Tobramycin, Dexamethasone Drug Combination
  • Tobramycin-Dexamethasone Drug Combination
  • Tobramycin Dexamethasone Drug Combination
  • TobraDex
  • TobraDex ST

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.745.432w.769.344w.650w
  2. D04w.210.500w.908.238w.650w
  3. D09w.408w.051.476w.600.800w.500w
  4. D26.310w.813w

AMA Style

References

  1. National Library of Medicine. Dexamethasone Drug Combination Tobramycin. Medical Subject Headings (MeSH). 2026. Unique ID D000078162. http://id.nlm.nih.gov/mesh/2026/D000078162
  2. Dexamethasone Drug Combination Tobramycin. In: Wikipedia. https://en.wikipedia.org/wiki/Tobramycin/dexamethasone
  3. Dexamethasone Drug Combination Tobramycin. In: Wikidata. https://www.wikidata.org/wiki/Q6147773
  4. Dexamethasone Drug Combination Tobramycin. In: PubChem Compound. CID 11949636. https://pubchem.ncbi.nlm.nih.gov/compound/11949636