Chemicals and Drugs

Deoxyribonuclease IV (Phage T4-Induced)

An enzyme which catalyzes the endonucleolytic cleavage of phosphodiester bonds at purinic or apyrimidinic sites (AP-sites) to produce 5'-Phosphooligonucleotide end products. The enzyme prefers single-stranded DNA (ssDNA) and was formerly classified as EC 3.1.4.30.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme which catalyzes the endonucleolytic cleavage of phosphodiester bonds at purinic or apyrimidinic sites (AP-sites) to produce 5'-Phosphooligonucleotide end products. The enzyme prefers single-stranded DNA (ssDNA) and was formerly classified as EC 3.1.4.30.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

3 entry terms
  • Deoxyriboendonuclease IV
  • Endonuclease IV
  • Redoxyendonuclease

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2004; use DEOXYRIBONUCLEASE IV (PHAGE T4-INDUCED) (NM) 1987-2002

MeSH Record

Previous Indexing

  • Endodeoxyribonucleases (1987-2003)

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References

  1. National Library of Medicine. Deoxyribonuclease IV (Phage T4-Induced). Medical Subject Headings (MeSH). 2026. Unique ID D043223. http://id.nlm.nih.gov/mesh/2026/D043223
  2. Deoxyribonuclease IV (Phage T4-Induced). In: Wikipedia. https://en.wikipedia.org/wiki/Deoxyribonuclease_IV
  3. Deoxyribonuclease IV (Phage T4-Induced). In: Wikidata. https://www.wikidata.org/wiki/Q5260075