Chemicals and Drugs

Dehydroepiandrosterone Sulfate

The circulating form of a major C19 steroid produced primarily by the ADRENAL CORTEX. DHEA sulfate serves as a precursor for TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The circulating form of a major C19 steroid produced primarily by the ADRENAL CORTEX. DHEA sulfate serves as a precursor for TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE.

Chemical Identity

Chemical Information

Molecular Formula
C19H28O5S
Molecular Weight
368.5 g/mol
CAS Registry No.
651-48-9
IUPAC Name
[(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] hydrogen sulfate
InChIKey
CZWCKYRVOZZJNM-USOAJAOKSA-N
SMILES
C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC=C4[C@@]3(CC[C@@H](C4)OS(=O)(=O)O)C
MeSH Unique ID
D019314
Source
PubChem CID 12594

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

9 entry terms
  • DHA Sulfate
  • DHEA Sulfate
  • Dehydroisoandrosterone Sulfate
  • Prasterone Sulfate
  • Sulfate, DHA
  • Sulfate, DHEA
  • Sulfate, Dehydroepiandrosterone
  • Sulfate, Dehydroisoandrosterone
  • Sulfate, Prasterone

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

97; was DEHYDROEPIANDROSTERONE SULFATE (NM) 1978-96

MeSH Record

Previous Indexing

  • Prasterone/analogs & derivatives (1978-1996)
  • Sulfuric Acids (1978-1980)

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.054.079.429.625w.300w
  2. D04w.210.500w.578.502w.400w.300w
  3. D06.472w.040.502w.400w.300w
  4. D06.472w.334.851w.968.952w.300w

AMA Style

References

  1. National Library of Medicine. Dehydroepiandrosterone Sulfate. Medical Subject Headings (MeSH). 2026. Unique ID D019314. http://id.nlm.nih.gov/mesh/2026/D019314
  2. Dehydroepiandrosterone Sulfate. In: Wikipedia. https://en.wikipedia.org/wiki/Dehydroepiandrosterone_sulfate
  3. Dehydroepiandrosterone Sulfate. In: Wikidata. https://www.wikidata.org/wiki/Q2505402
  4. Dehydroepiandrosterone Sulfate. In: PubChem Compound. CID 12594. https://pubchem.ncbi.nlm.nih.gov/compound/12594