Chemicals and Drugs

Dectin-1

A C-type lectin that functions as a pattern recognition receptor on DENDRITIC CELLS and other immune cells. It is specific for beta-1,-linked and beta 1,6-linked GLUCANS that constitute the CELL WALL of pathogenic bacteria and fungi, and is essential for the TOLL-LIKE RECEPTOR 2 INNATE INFLAMMATORY RESPONSE and activation of NF-KAPPA-B.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A C-type lectin that functions as a pattern recognition receptor on DENDRITIC CELLS and other immune cells. It is specific for beta-1,-linked and beta 1,6-linked GLUCANS that constitute the CELL WALL of pathogenic bacteria and fungi, and is essential for the TOLL-LIKE RECEPTOR 2 INNATE INFLAMMATORY RESPONSE and activation of NF-KAPPA-B.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

3 entry terms
  • CD369 Antigen
  • Dectin 1
  • Dectin1

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2026 (2000)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.503w.280.343
  2. D12.776w.543w.750w.705w.910w.111

AMA Style

References

  1. National Library of Medicine. Dectin-1. Medical Subject Headings (MeSH). 2026. Unique ID D000099181. http://id.nlm.nih.gov/mesh/2026/D000099181
  2. Dectin-1. In: Wikidata. https://www.wikidata.org/wiki/Q21113761