Chemicals and Drugs

Deamino Arginine Vasopressin

A synthetic analog of the pituitary hormone, ARGININE VASOPRESSIN. Its action is mediated by the VASOPRESSIN receptor V2. It has prolonged antidiuretic activity, but little pressor effects. It also modulates levels of circulating FACTOR VIII and VON WILLEBRAND FACTOR.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A synthetic analog of the pituitary hormone, ARGININE VASOPRESSIN. Its action is mediated by the VASOPRESSIN receptor V2. It has prolonged antidiuretic activity, but little pressor effects. It also modulates levels of circulating FACTOR VIII and VON WILLEBRAND FACTOR.

Chemical Identity

Chemical Information

Molecular Formula
C46H64N14O12S2
Molecular Weight
1069.2 g/mol
CAS Registry No.
16679-58-6
IUPAC Name
(2S)-N-[(2R)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
InChIKey
NFLWUMRGJYTJIN-PNIOQBSNSA-N
SMILES
C1C[C@H](N(C1)C(=O)[C@@H]2CSSCCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)C(=O)N[C@H](CCCN=C(N)N)C(=O)NCC(=O)N
MeSH Unique ID
D003894
Source
PubChem CID 5311065

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

28 entry terms
  • 1-Deamino-8-D-arginine Vasopressin
  • 1-Desamino-8-arginine Vasopressin
  • Desmopressin
  • Vasopressin, Deamino Arginine
  • Arginine Vasopressin, Deamino
  • Vasopressin, 1-Deamino-8-D-arginine
  • Vasopressin, 1-Desamino-8-arginine
  • Adiuretin
  • Adiuretin SD
  • Apo-Desmopressin
  • DDAVP
  • Desmogalen
  • Desmopressin Acetate
  • Desmopressin Monoacetate
  • Desmopressin Monoacetate, Trihydrate
  • Desmopressine Ferring
  • Desmospray
  • Desmotabs
  • Minirin
  • Minurin
  • Nocutil
  • Octim
  • Octostim
  • Acetate, Desmopressin
  • Ferring, Desmopressine
  • Monoacetate, Desmopressin
  • Monoacetate, Trihydrate Desmopressin
  • Trihydrate Desmopressin Monoacetate

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

86(79); was see under ARGIPRESSIN 1979-85; was DEAMINO ARGININE VASOPRESSIN see under VASOPRESSIN 1975-78

MeSH Record

Previous Indexing

  • Arginine (1966-1974)
  • Vasopressins (1966-1974)

MeSH Hierarchy

Tree Numbers

  1. D06.472w.699w.631.692.781.100w.250w
  2. D12.644w.400w.900.100w.250w
  3. D12.644w.456w.925.100w.250w
  4. D12.644w.548w.691.692.781.100w.250w
  5. D12.776w.631w.650w.937.100w.250w

MeSH Record

NLM Classification

WK 520

AMA Style

References

  1. National Library of Medicine. Deamino Arginine Vasopressin. Medical Subject Headings (MeSH). 2026. Unique ID D003894. http://id.nlm.nih.gov/mesh/2026/D003894
  2. Deamino Arginine Vasopressin. In: Wikipedia. https://en.wikipedia.org/wiki/Desmopressin
  3. Deamino Arginine Vasopressin. In: Wikidata. https://www.wikidata.org/wiki/Q241006
  4. Deamino Arginine Vasopressin. In: PubChem Compound. CID 5311065. https://pubchem.ncbi.nlm.nih.gov/compound/5311065