Chemicals and Drugs

DOM 2,5-Dimethoxy-4-Methylamphetamine

A psychedelic phenyl isopropylamine derivative, commonly called DOM, whose mood-altering effects and mechanism of action may be similar to those of LSD.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A psychedelic phenyl isopropylamine derivative, commonly called DOM, whose mood-altering effects and mechanism of action may be similar to those of LSD.

Chemical Identity

Chemical Information

Molecular Formula
C12H19NO2
Molecular Weight
209.28 g/mol
CAS Registry No.
43061-13-8
IUPAC Name
(2R)-1-(2,5-dimethoxy-4-methylphenyl)propan-2-amine
InChIKey
NTJQREUGJKIARY-SECBINFHSA-N
SMILES
CC1=CC(=C(C=C1OC)C[C@@H](C)N)OC
MeSH Unique ID
D004290
Source
PubChem CID 11735949

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

14 entry terms
  • 1-(2,5-Dimethoxy-4-Methylphenyl)-2-Aminopropane
  • 2 5 DOM
  • 2,5-Dimethoxy-4-Methylamphetamine
  • 2,5-Dimethoxy-4-Methylamphetamine (DOM)
  • 2,5 Dimethoxy 4 Methylamphetamine
  • 2,5-Dimethoxy-4-Methylamphetamine, DOM
  • DOM 2,5 Dimethoxy 4 Methylamphetamine
  • 2,5-Dimethoxy-4-Methylamphetamine Hydrochloride, (+,-)-Isomer
  • 2,5-Dimethoxy-4-Methylamphetamine Hydrochloride, (R)-Isomer
  • 2,5-Dimethoxy-4-Methylamphetamine Hydrochloride, (S)-Isomer
  • 2,5-Dimethoxy-4-Methylamphetamine, (+,-)-Isomer
  • 2,5-Dimethoxy-4-Methylamphetamine, (R)-Isomer
  • 2,5-Dimethoxy-4-Methylamphetamine, (S)-Isomer
  • 2,5-Dimethoxy-4-Methylamphetamine, Hydrochloride

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2024; was 2,5-Dimethoxy-4-Methylamphetamine 2000-2023

MeSH Hierarchy

Tree Number

  1. D02w.092w.471.683w.152w.391

AMA Style

References

  1. National Library of Medicine. DOM 2,5-Dimethoxy-4-Methylamphetamine. Medical Subject Headings (MeSH). 2026. Unique ID D004290. http://id.nlm.nih.gov/mesh/2026/D004290
  2. DOM 2,5-Dimethoxy-4-Methylamphetamine. In: Wikidata. https://www.wikidata.org/wiki/Q209257
  3. DOM 2,5-Dimethoxy-4-Methylamphetamine. In: PubChem Compound. CID 11735949. https://pubchem.ncbi.nlm.nih.gov/compound/11735949