Structured Summary
Abstract
A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms but may be present in higher organisms. Use also for a more complex form of DNA polymerase III designated as DNA polymerase III* or pol III* which is 15 times more active biologically than DNA polymerase I in the synthesis of DNA. This polymerase has both 3'-5' and 5'-3' exonuclease activities, is inhibited by sulfhydryl reagents, and has the same template-primer dependence as pol II.
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Classification
Broader headings
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Synonyms
6 entry terms
- DNA Pol III
- DNA Polymerase delta
- DNA-Dependent DNA Polymerase III
- DNA Dependent DNA Polymerase III
- Polymerase III, DNA
- Polymerase delta, DNA
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
91(77); for DNA POLYMERASE DELTA use DNA POLYMERASE III (NM) 1980-97
MeSH Record
Previous Indexing
- DNA Nucleotidyltransferases (1968-1976)
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AMA Style
References
- National Library of Medicine. DNA Polymerase III. Medical Subject Headings (MeSH). 2026. Unique ID D004258. http://id.nlm.nih.gov/mesh/2026/D004258
- DNA Polymerase III. In: Wikipedia. https://en.wikipedia.org/wiki/DNA_polymerase_III_holoenzyme
- DNA Polymerase III. In: Wikidata. https://www.wikidata.org/wiki/Q21119136