Chemicals and Drugs

DNA Nucleotidylexotransferase

A non-template-directed DNA polymerase normally found in vertebrate thymus and bone marrow. It catalyzes the elongation of oligo- or polydeoxynucleotide chains and is widely used as a tool in the differential diagnosis of acute leukemias in man. EC 2.7.7.31.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A non-template-directed DNA polymerase normally found in vertebrate thymus and bone marrow. It catalyzes the elongation of oligo- or polydeoxynucleotide chains and is widely used as a tool in the differential diagnosis of acute leukemias in man. EC 2.7.7.31.

MeSH Record

Classification

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MeSH Record

Synonyms

20 entry terms
  • Deoxynucleotidyl Transferase
  • Deoxynucleotidyltransferase
  • Desoxynucleotidyl Transferase
  • Desoxynucleotidyltransferase
  • Terminal Addition Enzyme
  • Terminal Deoxynucleotidyl Transferase
  • Terminal Deoxyribonucleotidyl Transferase
  • Terminal Deoxyribonucleotidyltransferase
  • Addition Enzyme, Terminal
  • Deoxynucleotidyl Transferase, Terminal
  • Deoxyribonucleotidyl Transferase, Terminal
  • Deoxyribonucleotidyltransferase, Terminal
  • Enzyme, Terminal Addition
  • Nucleotidylexotransferase, DNA
  • Transferase, Deoxynucleotidyl
  • Transferase, Desoxynucleotidyl
  • Transferase, Terminal Deoxynucleotidyl
  • Transferase, Terminal Deoxyribonucleotidyl
  • Tdt Antigen
  • Antigen, Tdt

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

89(79); was see under DNA NUCLEOTIDYLTRANSFERASES 1979-88

MeSH Record

Previous Indexing

  • DNA Nucleotidyltransferases (1968-1978)
  • Transferases (1966-1967)

MeSH Hierarchy

Tree Number

MeSH Record

NLM Classification

QU 141

AMA Style

References

  1. National Library of Medicine. DNA Nucleotidylexotransferase. Medical Subject Headings (MeSH). 2026. Unique ID D004253. http://id.nlm.nih.gov/mesh/2026/D004253
  2. DNA Nucleotidylexotransferase. In: Wikidata. https://www.wikidata.org/wiki/Q24778329