Structured Summary
Abstract
A fungal metabolite that blocks cytoplasmic cleavage by blocking formation of contractile microfilament structures resulting in multinucleated cell formation, reversible inhibition of cell movement, and the induction of cellular extrusion. Additional reported effects include the inhibition of actin polymerization, DNA synthesis, sperm motility, glucose transport, thyroid secretion, and growth hormone release.
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Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
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History Note
90
MeSH Record
Previous Indexing
- Cytochalasins (1973-1989)
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References
- National Library of Medicine. Cytochalasin D. Medical Subject Headings (MeSH). 2026. Unique ID D015638. http://id.nlm.nih.gov/mesh/2026/D015638
- Cytochalasin D. In: Wikipedia. https://en.wikipedia.org/wiki/Cytochalasin_D
- Cytochalasin D. In: Wikidata. https://www.wikidata.org/wiki/Q5201339