Chemicals and Drugs

Cystine-Knot Miniproteins

A structurally-related family of small proteins that form a stable tertiary fold pattern which is supported by a series of disulfide bonds. The arrangement of disulfide bonds between the CYSTEINE moieties results in a knotted structure which is unique to this family of proteins.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A structurally-related family of small proteins that form a stable tertiary fold pattern which is supported by a series of disulfide bonds. The arrangement of disulfide bonds between the CYSTEINE moieties results in a knotted structure which is unique to this family of proteins.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

3 entry terms
  • Knottin
  • Knottins
  • Cystine Knot Miniproteins

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2011

MeSH Hierarchy

Tree Numbers

  1. D12.644w.132
  2. D12.776w.217

AMA Style

References

  1. National Library of Medicine. Cystine-Knot Miniproteins. Medical Subject Headings (MeSH). 2026. Unique ID D057771. http://id.nlm.nih.gov/mesh/2026/D057771
  2. Cystine-Knot Miniproteins. In: Wikidata. https://www.wikidata.org/wiki/Q76642135