Diseases

Cystic Fibrosis

An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

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Classification

Broader headings

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MeSH Record

See Also

MeSH Record

Synonyms

10 entry terms
  • Mucoviscidosis
  • Fibrosis, Cystic
  • Cystic Fibrosis of Pancreas
  • Fibrocystic Disease of Pancreas
  • Pancreatic Cystic Fibrosis
  • Pulmonary Cystic Fibrosis
  • Cystic Fibrosis, Pancreatic
  • Cystic Fibrosis, Pulmonary
  • Pancreas Fibrocystic Disease
  • Pancreas Fibrocystic Diseases

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

Indexing Annotation

a specific disease entity: do not use for fibrocystic states of various organs

MeSH Record

History Note

67; was PANCREATIC CYSTIC FIBROSIS 1963-66

MeSH Hierarchy

Tree Numbers

  1. C06w.689w.202w
  2. C08w.381.187w
  3. C16w.320w.190w
  4. C16w.614.213w

AMA Style

References

  1. National Library of Medicine. Cystic Fibrosis. Medical Subject Headings (MeSH). 2026. Unique ID D003550. http://id.nlm.nih.gov/mesh/2026/D003550
  2. Cystic Fibrosis. In: Wikipedia. https://en.wikipedia.org/wiki/Cystic_fibrosis
  3. Cystic Fibrosis. In: Wikidata. https://www.wikidata.org/wiki/Q178194