Structured Summary
Abstract
A multifunctional pyridoxal phosphate enzyme. In the second stage of cysteine biosynthesis it catalyzes the reaction of homocysteine with serine to form cystathionine with the elimination of water. Deficiency of this enzyme leads to HYPERHOMOCYSTEINEMIA and HOMOCYSTINURIA. EC 4.2.1.22.
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Classification
Broader headings
Related Concepts
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See Also
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Synonyms
8 entry terms
- Cystathionine Synthetase
- Serine Sulfhydrase
- beta-Thionase
- Cystathionine beta Synthase
- Sulfhydrase, Serine
- Synthetase, Cystathionine
- beta Thionase
- beta-Synthase, Cystathionine
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
/defic: consider also HOMOCYSTINURIA or HYPERHOMOCYSTEINEMIA
MeSH Record
History Note
1991(1975)
MeSH Record
Previous Indexing
- Homocysteine (1973-1974)
- Hydro-Lyases (1973-1974)
- Serine (1973-1974)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Cystathionine beta-Synthase. Medical Subject Headings (MeSH). 2026. Unique ID D003541. http://id.nlm.nih.gov/mesh/2026/D003541
- Cystathionine beta-Synthase. In: Wikidata. https://www.wikidata.org/wiki/Q24767109