Structured Summary
Abstract
A group of closely related cyclic undecapeptides from the fungi Trichoderma polysporum and Cylindocarpon lucidum. They have some antineoplastic and antifungal action and significant immunosuppressive effects. Cyclosporins have been proposed as adjuvants in tissue and organ transplantation to suppress graft rejection.
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Classification
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
1 entry terms
- Cyclosporines
MeSH Record
Aspects Covered
27 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
Indexing Annotation
do not confuse with CYCLOSPORINE, a specific drug
MeSH Record
History Note
82
MeSH Record
Previous Indexing
- Immunosuppressive Agents (1966-1981)
- Peptides (1966-1970)
- Peptides, Cyclic (1971-1981)
MeSH Hierarchy
Tree Numbers
MeSH Record
NLM Classification
QW 955
AMA Style
References
- National Library of Medicine. Cyclosporins. Medical Subject Headings (MeSH). 2026. Unique ID D003524. http://id.nlm.nih.gov/mesh/2026/D003524
- Cyclosporins. In: Wikipedia. https://en.wikipedia.org/wiki/Cyclosporins
- Cyclosporins. In: Wikidata. https://www.wikidata.org/wiki/Q5199020