Chemicals and Drugs

Cyclin D1

Protein encoded by the bcl-1 gene which plays a critical role in regulating the cell cycle. Overexpression of cyclin D1 is the result of bcl-1 rearrangement, a t(11;14) translocation, and is implicated in various neoplasms.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Protein encoded by the bcl-1 gene which plays a critical role in regulating the cell cycle. Overexpression of cyclin D1 is the result of bcl-1 rearrangement, a t(11;14) translocation, and is implicated in various neoplasms.

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Classification

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See Also

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Synonyms

21 entry terms
  • CCND1 Protein
  • PRAD1 Protein
  • Proto-Oncogene Products bcl-1
  • Proto-Oncogene Protein bcl-1
  • Proto-Oncogene Proteins c-bcl-1
  • bcl-1 Proto-Oncogene Products
  • bcl-1 Proto-Oncogene Proteins
  • bcl1 Proto-Oncogene Proteins
  • c-bcl-1 Proteins
  • Proto Oncogene Products bcl 1
  • Proto Oncogene Protein bcl 1
  • Proto Oncogene Proteins c bcl 1
  • Proto-Oncogene Products, bcl-1
  • Proto-Oncogene Proteins, bcl-1
  • Proto-Oncogene Proteins, bcl1
  • bcl 1 Proto Oncogene Products
  • bcl 1 Proto Oncogene Proteins
  • bcl-1, Proto-Oncogene Protein
  • bcl1 Proto Oncogene Proteins
  • c bcl 1 Proteins
  • c-bcl-1, Proto-Oncogene Proteins

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

98; use CYCLIN D1 (NM) 1990-97

MeSH Record

Previous Indexing

  • Cyclins (1991-1997)
  • Oncogene Proteins (1991-1997)
  • Proto-Oncogene Proteins (1990-1997)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Cyclin D1. Medical Subject Headings (MeSH). 2026. Unique ID D019938. http://id.nlm.nih.gov/mesh/2026/D019938
  2. Cyclin D1. In: Wikidata. https://www.wikidata.org/wiki/Q5198270