Structured Summary
Abstract
Cyclin-dependent kinase 4 is a key regulator of G1 PHASE of the CELL CYCLE. It partners with CYCLIN D to phosphorylate RETINOBLASTOMA PROTEIN. CDK4 activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P16.
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Synonyms
14 entry terms
- Cdk4 Cyclin-Dependent Kinase
- Cdk4 Protein
- Cdk4 Protein Kinase
- Cell Division Protein Kinase 4
- Cyclin D-Dependent Kinase CDK4
- PSK-J3 Kinase
- p34PSK-J3 Kinase
- Cdk4 Cyclin Dependent Kinase
- Cyclin D Dependent Kinase CDK4
- Cyclin Dependent Kinase 4
- Cyclin-Dependent Kinase, Cdk4
- PSK J3 Kinase
- Protein Kinase, Cdk4
- p34PSK J3 Kinase
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006(1992)
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AMA Style
References
- National Library of Medicine. Cyclin-Dependent Kinase 4. Medical Subject Headings (MeSH). 2026. Unique ID D051358. http://id.nlm.nih.gov/mesh/2026/D051358
- Cyclin-Dependent Kinase 4. In: Wikidata. https://www.wikidata.org/wiki/Q5198250