Chemicals and Drugs

Cyclic AMP Receptor Protein

A transcriptional regulator in prokaryotes which, when activated by binding cyclic AMP, acts at several promoters. Cyclic AMP receptor protein was originally identified as a catabolite gene activator protein. It was subsequently shown to regulate several functions unrelated to catabolism, and to be both a negative and a positive regulator of transcription. Cell surface cyclic AMP receptors are not included (CYCLIC AMP RECEPTORS), nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins, which are the regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A transcriptional regulator in prokaryotes which, when activated by binding cyclic AMP, acts at several promoters. Cyclic AMP receptor protein was originally identified as a catabolite gene activator protein. It was subsequently shown to regulate several functions unrelated to catabolism, and to be both a negative and a positive regulator of transcription. Cell surface cyclic AMP receptors are not included (CYCLIC AMP RECEPTORS), nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins, which are the regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASES.

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Classification

Broader headings

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See Also

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Synonyms

27 entry terms
  • Activator Protein, Catabolite
  • Activator Proteins, Catabolite
  • Activator, Catabolic Gene
  • Activators, Catabolic Gene
  • Catabolic Gene Activator
  • Catabolic Gene Activators
  • Catabolite Activator Protein
  • Catabolite Activator Proteins
  • Catabolite Gene Activator Protein
  • Catabolite Gene Activator Proteins
  • Catabolite Regulator Protein
  • Catabolite Regulator Proteins
  • Cyclic AMP Receptor Proteins
  • Gene Activator, Catabolic
  • Gene Activators, Catabolic
  • Protein, Catabolite Activator
  • Protein, Catabolite Regulator
  • Proteins, Catabolite Activator
  • Proteins, Catabolite Regulator
  • Regulator Protein, Catabolite
  • Regulator Proteins, Catabolite
  • cAMP Receptor Protein
  • cAMP Receptor Proteins
  • Protein, cAMP Receptor
  • Proteins, cAMP Receptor
  • Receptor Protein, cAMP
  • Receptor Proteins, cAMP

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

94; was CATABOLITE GENE ACTIVATOR PROTEINS 1988-93; CYCLIC AMP RECEPTOR PROTEIN was see CATABOLITE GENE ACTIVATOR PROTEIN 1990-93; CATABOLITE GENE ACTIVATOR PROTEIN was see RECEPTORS, CYCLIC AMP 1987; CATABOLITE ACTIVATOR PROTEIN was see RECEPTORS, CYCLIC AMP 1987; CATABOLIC GENE ACTIVATORS was see RECEPTORS, CYCLIC AMP 1977-87

MeSH Record

Previous Indexing

  • Amino Acid Sequence (1975-1987)
  • Bacterial Proteins (1972-1987)
  • Base Sequence (1980-1987)
  • Receptors, Cyclic AMP (1980-1993)
  • Transcription Factors (1980-1987)
  • Transcription, Genetic (1978-1987)

MeSH Hierarchy

Tree Number

  1. D12.776w.930w.165w

AMA Style

References

  1. National Library of Medicine. Cyclic AMP Receptor Protein. Medical Subject Headings (MeSH). 2026. Unique ID D002373. http://id.nlm.nih.gov/mesh/2026/D002373
  2. Cyclic AMP Receptor Protein. In: Wikipedia. https://en.wikipedia.org/wiki/CAMP_receptor_protein
  3. Cyclic AMP Receptor Protein. In: Wikidata. https://www.wikidata.org/wiki/Q5008668