Chemicals and Drugs

Cyclic ADP-Ribose

A pyridine nucleotide that mobilizes CALCIUM. It is synthesized from nicotinamide adenine dinucleotide (NAD) by ADP RIBOSE CYCLASE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A pyridine nucleotide that mobilizes CALCIUM. It is synthesized from nicotinamide adenine dinucleotide (NAD) by ADP RIBOSE CYCLASE.

Chemical Identity

Chemical Information

Molecular Formula
C15H21N5O13P2
Molecular Weight
541.30 g/mol
CAS Registry No.
119340-53-3
IUPAC Name
(2R,3R,4S,5R,13R,14S,15R,16R)-8,10-dihydroxy-24-imino-8,10-dioxo-7,9,11,25,26-pentaoxa-1,17,19,22-tetraza-8lambda5,10lambda5-diphosphapentacyclo[18.3.1.12,5.113,16.017,21]hexacosa-18,20,22-triene-3,4,14,15-tetrol
InChIKey
BQOHYSXSASDCEA-KEOHHSTQSA-N
SMILES
C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C3N=CN(C4=N)[C@H]5[C@@H]([C@@H]([C@H](O5)COP(=O)(OP(=O)(O1)O)O)O)O)O)O
MeSH Unique ID
D036563
Source
PubChem CID 123847

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

9 entry terms
  • Adenosine Diphosphate Ribose, Cyclic
  • Cyclic ADPribose
  • Cyclic Adenosine Diphosphate Ribose
  • cADP-Ribose
  • cADPR
  • ADP-Ribose, Cyclic
  • ADPribose, Cyclic
  • Cyclic ADP Ribose
  • cADP Ribose

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2003; use CYCLIC ADP-RIBOSE (NM)1989-2002

MeSH Record

Previous Indexing

  • Adenosine Diphosphate Ribose (1989-2002)

MeSH Hierarchy

Tree Numbers

  1. D03w.633.100.759.646.138.124w.070.125w.195w
  2. D09w.408w.620w.569.070.125w.195w
  3. D13.695w.667.138.124w.070.125w.195w
  4. D13.695w.827w.068.124w.070.125w.195w
  5. D13.695w.827w.708.070.125w.195w

AMA Style

References

  1. National Library of Medicine. Cyclic ADP-Ribose. Medical Subject Headings (MeSH). 2026. Unique ID D036563. http://id.nlm.nih.gov/mesh/2026/D036563
  2. Cyclic ADP-Ribose. In: Wikipedia. https://en.wikipedia.org/wiki/Cyclic_ADP-ribose
  3. Cyclic ADP-Ribose. In: Wikidata. https://www.wikidata.org/wiki/Q2467043
  4. Cyclic ADP-Ribose. In: PubChem Compound. CID 123847. https://pubchem.ncbi.nlm.nih.gov/compound/123847