Chemicals and Drugs

Crotoxin

A specific complex of toxic proteins from the venom of Crotalus durissus terrificus (South American rattlesnake). It can be separated into a phospholipase A and crotapotin fragment; the latter consists of three different amino acid chains, potentiates the enzyme, and is specifically neurotoxic.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A specific complex of toxic proteins from the venom of Crotalus durissus terrificus (South American rattlesnake). It can be separated into a phospholipase A and crotapotin fragment; the latter consists of three different amino acid chains, potentiates the enzyme, and is specifically neurotoxic.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

3 entry terms
  • Crotapotin
  • Crotoxin A
  • Crotoxin B

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

from a So. Amer. rattlesnake; /antag permitted but consider also ANTIVENINS

MeSH Record

History Note

91(78); was see under CROTALID VENOMS 1978-90

MeSH Record

Previous Indexing

  • Snake Venoms (1975-1977)
  • Snakes (1966-1974)
  • Venoms (1966-1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Crotoxin. Medical Subject Headings (MeSH). 2026. Unique ID D003439. http://id.nlm.nih.gov/mesh/2026/D003439
  2. Crotoxin. In: Wikipedia. https://en.wikipedia.org/wiki/Crotoxin
  3. Crotoxin. In: Wikidata. https://www.wikidata.org/wiki/Q5792231