Diseases

Crigler-Najjar Syndrome

A familial form of congenital hyperbilirubinemia transmitted as an autosomal recessive trait. It is characterized by icterus and brain damage caused by a glucuronyl transferase deficiency in the liver and faulty bilirubin conjugation.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A familial form of congenital hyperbilirubinemia transmitted as an autosomal recessive trait. It is characterized by icterus and brain damage caused by a glucuronyl transferase deficiency in the liver and faulty bilirubin conjugation.

MeSH Record

Classification

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

14 entry terms
  • Crigler Najjar Syndrome
  • Crigler-Najar Syndrome
  • Familial Nonhemolytic Unconjugated Hyperbilirubinemia
  • Hereditary Unconjugated Hyperbilirubinemia
  • Crigler Najar Syndrome
  • Crigler Najjar Syndromes
  • Hereditary Unconjugated Hyperbilirubinemias
  • Hyperbilirubinemia, Hereditary Unconjugated
  • Najjar Syndrome, Crigler
  • Syndrome, Crigler Najjar
  • Unconjugated Hyperbilirubinemia, Hereditary
  • Crigler Najjar Syndrome, Type 1
  • Crigler-Najjar Syndrome, Type I
  • Crigler Najjar Syndrome, Type I

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

91(75); was see under HYPERBILIRUBINEMIA, HEREDITARY 1975-90

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Crigler-Najjar Syndrome. Medical Subject Headings (MeSH). 2026. Unique ID D003414. http://id.nlm.nih.gov/mesh/2026/D003414
  2. Crigler-Najjar Syndrome. In: Wikipedia. https://en.wikipedia.org/wiki/Crigler%E2%80%93Najjar_syndrome
  3. Crigler-Najjar Syndrome. In: Wikidata. https://www.wikidata.org/wiki/Q1140000