Structured Summary
Abstract
A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
39 entry terms
- CJD (Creutzfeldt-Jakob Disease)
- Creutzfeldt Jacob Disease
- Creutzfeldt-Jakob Disease
- Jakob-Creutzfeldt Disease
- Jakob-Creutzfeldt Syndrome
- Spongiform Encephalopathy, Subacute
- CJD (Creutzfeldt Jakob Disease)
- Creutzfeldt Jakob Disease
- Creutzfeldt Jakob Syndrome
- Disease, Creutzfeldt Jacob
- Disease, Creutzfeldt-Jakob
- Disease, Jakob-Creutzfeldt
- Encephalopathies, Subacute Spongiform
- Encephalopathy, Subacute Spongiform
- Jacob Disease, Creutzfeldt
- Jakob Creutzfeldt Disease
- Jakob Creutzfeldt Syndrome
- Spongiform Encephalopathies, Subacute
- Subacute Spongiform Encephalopathies
- Subacute Spongiform Encephalopathy
- Syndrome, Creutzfeldt-Jakob
- Syndrome, Jakob-Creutzfeldt
- Creutzfeldt-Jakob Disease, Familial
- Creutzfeldt-Jakob Disease, New Variant
- Creutzfeldt-Jakob Disease, Variant
- Familial Creutzfeldt-Jakob Disease
- New Variant Creutzfeldt-Jakob Disease
- V-CJD (Variant-Creutzfeldt-Jakob Disease)
- Variant Creutzfeldt-Jakob Disease
- Creutzfeldt Jakob Disease, Familial
- Creutzfeldt Jakob Disease, New Variant
- Creutzfeldt Jakob Disease, Variant
- Creutzfeldt-Jakob Diseases, Familial
- Disease, Familial Creutzfeldt-Jakob
- Familial Creutzfeldt Jakob Disease
- Familial Creutzfeldt-Jakob Diseases
- New Variant Creutzfeldt Jakob Disease
- V CJD (Variant Creutzfeldt Jakob Disease)
- Variant Creutzfeldt Jakob Disease
MeSH Record
Aspects Covered
36 allowable subheadings
Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, transmission, urine, veterinary, virology.
MeSH Record
History Note
1991; use JAKOB-CREUTZFELDT SYNDROME 1981-1990, use CREUTZFELDT-JAKOB DISEASE 1969-1980
MeSH Record
Previous Indexing
- Central Nervous System Diseases (1966-1968)
MeSH Hierarchy
Tree Numbers
MeSH Record
NLM Classification
WL 301
AMA Style
References
- National Library of Medicine. Creutzfeldt-Jakob Syndrome. Medical Subject Headings (MeSH). 2026. Unique ID D007562. http://id.nlm.nih.gov/mesh/2026/D007562
- Creutzfeldt-Jakob Syndrome. In: Wikipedia. https://en.wikipedia.org/wiki/Creutzfeldt%E2%80%93Jakob_disease
- Creutzfeldt-Jakob Syndrome. In: Wikidata. https://www.wikidata.org/wiki/Q49989