Chemicals and Drugs

Creatine Kinase

A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.

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MeSH Record

Synonyms

11 entry terms
  • ADP Phosphocreatine Phosphotransferase
  • ATP Creatine Phosphotransferase
  • Creatine Phosphokinase
  • Creatine Phosphotransferase, ATP
  • Kinase, Creatine
  • Phosphocreatine Phosphotransferase, ADP
  • Phosphokinase, Creatine
  • Phosphotransferase, ADP Phosphocreatine
  • Phosphotransferase, ATP Creatine
  • Macro-Creatine Kinase
  • Macro Creatine Kinase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Hierarchy

Tree Number

  1. D08.811w.913w.696w.640.150w

MeSH Record

NLM Classification

QU 141

AMA Style

References

  1. National Library of Medicine. Creatine Kinase. Medical Subject Headings (MeSH). 2026. Unique ID D003402. http://id.nlm.nih.gov/mesh/2026/D003402
  2. Creatine Kinase. In: Wikipedia. https://en.wikipedia.org/wiki/Creatine_kinase
  3. Creatine Kinase. In: Wikidata. https://www.wikidata.org/wiki/Q409458