Phenomena and Processes

CpG Islands

Areas of increased density of the dinucleotide sequence cytosine--phosphate diester--guanine. They form stretches of DNA several hundred to several thousand base pairs long. In humans there are about 45,000 CpG islands, mostly found at the 5' ends of genes. They are unmethylated except for those on the inactive X chromosome and some associated with imprinted genes.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Areas of increased density of the dinucleotide sequence cytosine--phosphate diester--guanine. They form stretches of DNA several hundred to several thousand base pairs long. In humans there are about 45,000 CpG islands, mostly found at the 5' ends of genes. They are unmethylated except for those on the inactive X chromosome and some associated with imprinted genes.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

12 entry terms
  • CpG-Rich Islands
  • CpG Island
  • CpG Rich Islands
  • CpG-Rich Island
  • Island, CpG
  • Island, CpG-Rich
  • Islands, CpG
  • Islands, CpG-Rich
  • CpG Clusters
  • Cluster, CpG
  • Clusters, CpG
  • CpG Cluster

MeSH Record

Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

96

MeSH Record

Previous Indexing

  • Base Sequence (1989-1995)
  • Dinucleoside Phosphates (1989-1995)

MeSH Hierarchy

Tree Numbers

  1. G02.111.570.080w.380.160w
  2. G05.360w.080w.380.160w
  3. G05.360w.340w.024.159w

AMA Style

References

  1. National Library of Medicine. CpG Islands. Medical Subject Headings (MeSH). 2026. Unique ID D018899. http://id.nlm.nih.gov/mesh/2026/D018899
  2. CpG Islands. In: Wikipedia. https://en.wikipedia.org/wiki/CpG_island
  3. CpG Islands. In: Wikidata. https://www.wikidata.org/wiki/Q1138360