Structured Summary
Abstract
The N-glucuronide conjugate of cotinine is a major urinary metabolite of NICOTINE. It thus serves as a biomarker of exposure to tobacco SMOKING. It has CNS stimulating properties.
Chemical Identity
Chemical Information
- Molecular Formula
- C10H12N2O
- Molecular Weight
- 176.21 g/mol
- CAS Registry No.
- 486-56-6
- IUPAC Name
- (5S)-1-methyl-5-pyridin-3-ylpyrrolidin-2-one
- InChIKey
- UIKROCXWUNQSPJ-VIFPVBQESA-N
- SMILES
- CN1[C@@H](CCC1=O)C2=CN=CC=C2
- MeSH Unique ID
- D003367
- Source
- PubChem CID 854019
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
1 entry terms
- Scotine
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
91(75); was see under PYRROLIDINONES 1975-90
MeSH Record
Previous Indexing
- Pyridines (1974)
- Pyrrolidinones (1969-1974)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Cotinine. Medical Subject Headings (MeSH). 2026. Unique ID D003367. http://id.nlm.nih.gov/mesh/2026/D003367
- Cotinine. In: Wikipedia. https://en.wikipedia.org/wiki/Cotinine
- Cotinine. In: Wikidata. https://www.wikidata.org/wiki/Q421177
- Cotinine. In: PubChem Compound. CID 854019. https://pubchem.ncbi.nlm.nih.gov/compound/854019