Chemicals and Drugs

Core Binding Factor beta Subunit

A non-DNA binding transcription factor that is a subunit of core binding factor. It forms heterodimeric complexes with CORE BINDING FACTOR ALPHA SUBUNITS, and regulates GENETIC TRANSCRIPTION of a variety of GENES involved primarily in CELL DIFFERENTIATION and CELL CYCLE progression.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A non-DNA binding transcription factor that is a subunit of core binding factor. It forms heterodimeric complexes with CORE BINDING FACTOR ALPHA SUBUNITS, and regulates GENETIC TRANSCRIPTION of a variety of GENES involved primarily in CELL DIFFERENTIATION and CELL CYCLE progression.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

4 entry terms
  • CBFB Protein
  • Core Binding Factor beta
  • Core Binding Factor beta Protein
  • Polyomavirus Enhancer Binding Protein 2, beta Subunit

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

see SCR for organism-specific terms

MeSH Record

History Note

2006(1987)

MeSH Record

Previous Indexing

  • DNA-Binding Proteins (1987-2005)
  • Transcription Factors (1987-2005)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Core Binding Factor beta Subunit. Medical Subject Headings (MeSH). 2026. Unique ID D050658. http://id.nlm.nih.gov/mesh/2026/D050658
  2. Core Binding Factor beta Subunit. In: Wikidata. https://www.wikidata.org/wiki/Q24773815