Publication Characteristics

Controlled Clinical Trial

A work that reports on a clinical trial involving one or more test treatments, at least one control treatment, specified outcome measures for evaluating the studied intervention, and a bias-free method for assigning patients to the test treatment. The treatment may be drugs, devices, or procedures studied for diagnostic, therapeutic, or prophylactic effectiveness. Control measures include placebos, active medicine, no-treatment, dosage forms and regimens, historical comparisons, etc. When randomization using mathematical techniques, such as the use of a random numbers table, is employed to assign patients to test or control treatments, the trial is characterized as a RANDOMIZED CONTROLLED TRIAL.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A work that reports on a clinical trial involving one or more test treatments, at least one control treatment, specified outcome measures for evaluating the studied intervention, and a bias-free method for assigning patients to the test treatment. The treatment may be drugs, devices, or procedures studied for diagnostic, therapeutic, or prophylactic effectiveness. Control measures include placebos, active medicine, no-treatment, dosage forms and regimens, historical comparisons, etc. When randomization using mathematical techniques, such as the use of a random numbers table, is employed to assign patients to test or control treatments, the trial is characterized as a RANDOMIZED CONTROLLED TRIAL.

MeSH Record

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MeSH Record

Indexing Annotation

this heading is used as a Publication Type; for original report of the conduct or results of a specific controlled clinical trial; a different heading CONTROLLED CLINICAL TRIALS AS TOPIC is used for general design, methodology, economics, etc. of clinical trials

MeSH Record

History Note

2008(1995)

MeSH Hierarchy

Tree Number

  1. V03.175.250.500

AMA Style

References

  1. National Library of Medicine. Controlled Clinical Trial. Medical Subject Headings (MeSH). 2026. Unique ID D018848. http://id.nlm.nih.gov/mesh/2026/D018848
  2. Controlled Clinical Trial. In: Wikidata. https://www.wikidata.org/wiki/Q58897597