Chemicals and Drugs

Connexin 43

A 43-kDa peptide which is a member of the connexin family of gap junction proteins. Connexin 43 is a product of a gene in the alpha class of connexin genes (the alpha-1 gene). It was first isolated from mammalian heart, but is widespread in the body including the brain.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A 43-kDa peptide which is a member of the connexin family of gap junction proteins. Connexin 43 is a product of a gene in the alpha class of connexin genes (the alpha-1 gene). It was first isolated from mammalian heart, but is widespread in the body including the brain.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

2 entry terms
  • Connexin43
  • Cx43

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

94; CONNEXIN 43 was (SY) to GAP JUNCTION PROTEIN 1991-93

MeSH Record

Previous Indexing

  • Membrane Proteins (1987-1993)

MeSH Hierarchy

Tree Number

  1. D12.776w.543w.585w.250w.200

AMA Style

References

  1. National Library of Medicine. Connexin 43. Medical Subject Headings (MeSH). 2026. Unique ID D018031. http://id.nlm.nih.gov/mesh/2026/D018031
  2. Connexin 43. In: Wikidata. https://www.wikidata.org/wiki/Q24776363