Chemicals and Drugs

Conjugate Vaccines

Semisynthetic vaccines consisting of polysaccharide antigens from microorganisms attached to protein carrier molecules. The carrier protein is recognized by macrophages and T-cells thus enhancing immunity. Conjugate vaccines induce antibody formation in people not responsive to polysaccharide alone, induce higher levels of antibody, and show a booster response on repeated injection.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Semisynthetic vaccines consisting of polysaccharide antigens from microorganisms attached to protein carrier molecules. The carrier protein is recognized by macrophages and T-cells thus enhancing immunity. Conjugate vaccines induce antibody formation in people not responsive to polysaccharide alone, induce higher levels of antibody, and show a booster response on repeated injection.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

3 entry terms
  • Conjugate Vaccine
  • Vaccines, Conjugate
  • Vaccine, Conjugate

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, microbiology, pharmacology, poisoning, radiation effects, standards, therapeutic use, toxicity, ultrastructure, urine, virology.

MeSH Record

Indexing Annotation

"induce antibody formation in people not responsive to polysaccharide alone"; semisynthetic vaccines; coord NIM with specific vaccine (IM)

MeSH Record

History Note

94

MeSH Record

Previous Indexing

  • Vaccines, Synthetic (1988-1993)
  • vaccine components/immunology (1984-1993)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Conjugate Vaccines. Medical Subject Headings (MeSH). 2026. Unique ID D018074. http://id.nlm.nih.gov/mesh/2026/D018074
  2. Conjugate Vaccines. In: Wikipedia. https://en.wikipedia.org/wiki/Conjugate_vaccine
  3. Conjugate Vaccines. In: Wikidata. https://www.wikidata.org/wiki/Q5161160