Analytical, Diagnostic and Therapeutic Techniques, and Equipment

Complement Hemolytic Activity Assay

A screening assay for circulating COMPLEMENT PROTEINS. Diluted SERUM samples are added to antibody-coated ERYTHROCYTES and the percentage of cell lysis is measured. The values are expressed by the so called CH50, in HEMOLYTIC COMPLEMENT units per milliliter, which is the dilution of serum required to lyse 50 percent of the erythrocytes in the assay.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A screening assay for circulating COMPLEMENT PROTEINS. Diluted SERUM samples are added to antibody-coated ERYTHROCYTES and the percentage of cell lysis is measured. The values are expressed by the so called CH50, in HEMOLYTIC COMPLEMENT units per milliliter, which is the dilution of serum required to lyse 50 percent of the erythrocytes in the assay.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

27 entry terms
  • CH50 Assay
  • Hemolytic Titration Assay
  • Assay, CH50
  • Assay, Hemolytic Titration
  • Assays, CH50
  • Assays, Hemolytic Titration
  • CH50 Assays
  • Hemolytic Titration Assays
  • Titration Assay, Hemolytic
  • Titration Assays, Hemolytic
  • CH(50)
  • Complement H50
  • Serum Complement Titer
  • Total Hemolytic Complement
  • Whole Complement Titer
  • Complement H50s
  • Complement, Total Hemolytic
  • Complements, Total Hemolytic
  • Hemolytic Complement, Total
  • Hemolytic Complements, Total
  • Serum Complement Titers
  • Titer, Serum Complement
  • Titer, Whole Complement
  • Titers, Serum Complement
  • Titers, Whole Complement
  • Total Hemolytic Complements
  • Whole Complement Titers

MeSH Record

Aspects Covered

10 allowable subheadings

Indexed with the subheadings classification, economics, ethics, history, instrumentation, methods, standards, statistics & numerical data, trends, veterinary.

MeSH Record

History Note

90

MeSH Record

Previous Indexing

  • Complement/analysis (1969-1989)

MeSH Hierarchy

Tree Numbers

  1. E01w.370.225.812.160.155w
  2. E01w.370.225.812.735.155w
  3. E05.200.812.160.155w
  4. E05.200.812.735.155w
  5. E05.478.594.160.150w
  6. E05.478.594.760.155w

AMA Style

References

  1. National Library of Medicine. Complement Hemolytic Activity Assay. Medical Subject Headings (MeSH). 2026. Unique ID D015941. http://id.nlm.nih.gov/mesh/2026/D015941
  2. Complement Hemolytic Activity Assay. In: Wikipedia. https://en.wikipedia.org/wiki/Total_complement_activity
  3. Complement Hemolytic Activity Assay. In: Wikidata. https://www.wikidata.org/wiki/Q7828100