Structured Summary
Abstract
Serologic tests based on inactivation of complement by the antigen-antibody complex (stage 1). Binding of free complement can be visualized by addition of a second antigen-antibody system such as red cells and appropriate red cell antibody (hemolysin) requiring complement for its completion (stage 2). Failure of the red cells to lyse indicates that a specific antigen-antibody reaction has taken place in stage 1. If red cells lyse, free complement is present indicating no antigen-antibody reaction occurred in stage 1.
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Synonyms
11 entry terms
- Complement Fixation Test
- Fixation Test, Complement
- Fixation Tests, Complement
- Test, Complement Fixation
- Tests, Complement Fixation
- Complement Absorption Test, Conglutinating
- Conglutinating Complement Absorption Test
- Conglutination Reaction
- Conglutination Reactions
- Reaction, Conglutination
- Reactions, Conglutination
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Aspects Covered
14 allowable subheadings
Indexed with the subheadings adverse effects, classification, economics, ethics, history, instrumentation, methods, mortality, nursing, psychology, standards, statistics & numerical data, trends, veterinary.
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History Note
CONGLUTINATION REACTION was heading 1975-96 (see under COMPLEMENT FIXATION TESTS 1975-90); COMPLEMENT ABSORPTION TEST, CONGLUTINATING was see CONGLUTINATION REACTION 1992-96
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NLM Classification
QY 265
AMA Style
References
- National Library of Medicine. Complement Fixation Tests. Medical Subject Headings (MeSH). 2026. Unique ID D003168. http://id.nlm.nih.gov/mesh/2026/D003168
- Complement Fixation Tests. In: Wikipedia. https://en.wikipedia.org/wiki/Complement_fixation_test
- Complement Fixation Tests. In: Wikidata. https://www.wikidata.org/wiki/Q904197