Structured Summary
Abstract
A 93-kDa serum glycoprotein encoded by C7 gene. It is a polypeptide chain with 28 disulfide bridges. In the formation of MEMBRANE ATTACK COMPLEX; C7 is the next component to bind the C5b-6 complex forming a trimolecular complex C5b-7 which is lipophilic, resembles an integral membrane protein, and serves as an anchor for the late complement components, C8 and C9.
MeSH Record
Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
6 entry terms
- C7 Complement
- Complement 7
- Complement Component 7
- C7, Complement
- Complement, C7
- Component 7, Complement
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006 (1975)
MeSH Record
Previous Indexing
- Chemotaxis (1966-1974)
- Complement (1968-1974)
- Neutrophils (1966-1974)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Complement C7. Medical Subject Headings (MeSH). 2026. Unique ID D003184. http://id.nlm.nih.gov/mesh/2026/D003184
- Complement C7. In: Wikidata. https://www.wikidata.org/wiki/Q21102480