Structured Summary
Abstract
A serum protein that regulates the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It binds as a cofactor to COMPLEMENT FACTOR I which then hydrolyzes the COMPLEMENT C4B in the CLASSICAL PATHWAY C3 CONVERTASE (C4bC2a).
MeSH Record
Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
16 entry terms
- C4b-Binding Protein
- C4b-C3b Inactivator Cofactor
- C4bC3bINA-Cofactor
- Complement 4b Binding Protein
- Complement C3b-C4b Inactivator Cofactor
- Complement Component 4b-Binding Protein
- C4b Binding Protein
- C4b C3b Inactivator Cofactor
- C4b-Binding Protein, Complement
- C4bC3bINA Cofactor
- Cofactor, C4b-C3b Inactivator
- Complement C3b C4b Inactivator Cofactor
- Complement C4b Binding Protein
- Complement Component 4b Binding Protein
- Protein, C4b-Binding
- Protein, Complement C4b-Binding
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006
MeSH Record
Previous Indexing
- Complement Inactivator Proteins (1981-2005)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Complement C4b-Binding Protein. Medical Subject Headings (MeSH). 2026. Unique ID D050716. http://id.nlm.nih.gov/mesh/2026/D050716
- Complement C4b-Binding Protein. In: Wikipedia. https://en.wikipedia.org/wiki/C4b-binding_protein
- Complement C4b-Binding Protein. In: Wikidata. https://www.wikidata.org/wiki/Q5008230