Chemicals and Drugs

Complement C2a

The COOH-terminal fragment of COMPLEMENT 2, released by the action of activated COMPLEMENT C1S. It is a SERINE PROTEASE. C2a combines with COMPLEMENT C4B to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The COOH-terminal fragment of COMPLEMENT 2, released by the action of activated COMPLEMENT C1S. It is a SERINE PROTEASE. C2a combines with COMPLEMENT C4B to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

7 entry terms
  • C2a Complement
  • Complement 2a
  • Complement C2 Fragment a
  • Complement C2a Fragment
  • C2a Fragment, Complement
  • C2a, Complement
  • Complement, C2a

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006 (1986)

MeSH Hierarchy

Tree Number

  1. D12.776w.124w.486.274.150.500

AMA Style

References

  1. National Library of Medicine. Complement C2a. Medical Subject Headings (MeSH). 2026. Unique ID D050678. http://id.nlm.nih.gov/mesh/2026/D050678
  2. Complement C2a. In: Wikidata. https://www.wikidata.org/wiki/Q76818661