Chemicals and Drugs

Cloprostenol

A synthetic prostaglandin F2alpha analog. The compound has luteolytic effects and is used for the synchronization of estrus in cattle.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A synthetic prostaglandin F2alpha analog. The compound has luteolytic effects and is used for the synchronization of estrus in cattle.

Chemical Identity

Chemical Information

Molecular Formula
C22H29ClO6
Molecular Weight
424.9 g/mol
CAS Registry No.
40665-92-7
IUPAC Name
(Z)-7-[(1R,2R,3R,5S)-2-[(E,3R)-4-(3-chlorophenoxy)-3-hydroxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoic acid
InChIKey
VJGGHXVGBSZVMZ-QIZQQNKQSA-N
SMILES
C1[C@@H]([C@@H]([C@H]([C@@H]1O)/C=C/[C@H](COC2=CC(=CC=C2)Cl)O)C/C=C\CCCC(=O)O)O
MeSH Unique ID
D003008
Source
PubChem CID 5311053

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • Cloprostenol Monosodium Salt
  • Cloprostenol Sodium
  • Estrumate
  • ICI-80,966
  • Oestrophan
  • ICI 80,966
  • ICI80,966
  • Monosodium Salt, Cloprostenol
  • Salt, Cloprostenol Monosodium
  • Sodium, Cloprostenol

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(79); was see under PROSTAGLANDINS F, SYNTHETIC 1979-90

MeSH Record

Previous Indexing

  • Prostaglandins F (1975-1977)
  • Prostaglandins F, Synthetic (1978)

MeSH Hierarchy

Tree Numbers

  1. D10w.251w.355w.255w.550w.775.500.175w
  2. D23.469.050w.175w.725w.775.500.175w
  3. D23.469.700.670.175w

AMA Style

References

  1. National Library of Medicine. Cloprostenol. Medical Subject Headings (MeSH). 2026. Unique ID D003008. http://id.nlm.nih.gov/mesh/2026/D003008
  2. Cloprostenol. In: Wikipedia. https://en.wikipedia.org/wiki/Cloprostenol
  3. Cloprostenol. In: Wikidata. https://www.wikidata.org/wiki/Q27076117
  4. Cloprostenol. In: PubChem Compound. CID 5311053. https://pubchem.ncbi.nlm.nih.gov/compound/5311053