Chemicals and Drugs

Clonidine

An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.

Chemical Identity

Chemical Information

Molecular Formula
C9H9Cl2N3
Molecular Weight
230.09 g/mol
CAS Registry No.
4205-90-7
IUPAC Name
N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine
InChIKey
GJSURZIOUXUGAL-UHFFFAOYSA-N
SMILES
C1CN=C(N1)NC2=C(C=CC=C2Cl)Cl
MeSH Unique ID
D003000
Source
PubChem CID 2803

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

27 entry terms
  • Clofenil
  • Klofenil
  • Catapres
  • Catapresan
  • Catapressan
  • Chlophazolin
  • Clofelin
  • Clonidine Dihydrochloride
  • Clonidine Hydrochloride
  • Clonidine Monohydrobromide
  • Clonidine Monohydrochloride
  • Clopheline
  • Dixarit
  • Gemiton
  • Hemiton
  • Isoglaucon
  • Klofelin
  • M-5041T
  • ST-155
  • Dihydrochloride, Clonidine
  • Hydrochloride, Clonidine
  • M 5041T
  • M5041T
  • Monohydrobromide, Clonidine
  • Monohydrochloride, Clonidine
  • ST 155
  • ST155

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

73(72)

MeSH Record

Previous Indexing

  • Antihypertensive Agents (1966-1971)
  • Imidazoles (1966-1971)

MeSH Hierarchy

Tree Number

  1. D03w.383.129w.308.436w.500w

AMA Style

References

  1. National Library of Medicine. Clonidine. Medical Subject Headings (MeSH). 2026. Unique ID D003000. http://id.nlm.nih.gov/mesh/2026/D003000
  2. Clonidine. In: Wikipedia. https://en.wikipedia.org/wiki/Clonidine
  3. Clonidine. In: Wikidata. https://www.wikidata.org/wiki/Q412221
  4. Clonidine. In: PubChem Compound. CID 2803. https://pubchem.ncbi.nlm.nih.gov/compound/2803