Chemicals and Drugs

Clofibrate

A fibric acid derivative used in the treatment of HYPERLIPOPROTEINEMIA TYPE III and severe HYPERTRIGLYCERIDEMIA. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A fibric acid derivative used in the treatment of HYPERLIPOPROTEINEMIA TYPE III and severe HYPERTRIGLYCERIDEMIA. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)

Chemical Identity

Chemical Information

Molecular Formula
C12H15ClO3
Molecular Weight
242.70 g/mol
CAS Registry No.
637-07-0
IUPAC Name
ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
InChIKey
KNHUKKLJHYUCFP-UHFFFAOYSA-N
SMILES
CCOC(=O)C(C)(C)OC1=CC=C(C=C1)Cl
MeSH Unique ID
D002994
Source
PubChem CID 2796

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • Clofibric Acid, Ethyl Ester
  • Ethyl Chlorophenoxyisobutyrate
  • Chlorophenoxyisobutyrate, Ethyl
  • Athromidin
  • Atromid
  • Atromid S
  • Miscleron
  • Miskleron

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

72(69)

MeSH Record

Previous Indexing

  • Anticholesteremic Agents (1966-1968)
  • Propionates (1966-1968)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Clofibrate. Medical Subject Headings (MeSH). 2026. Unique ID D002994. http://id.nlm.nih.gov/mesh/2026/D002994
  2. Clofibrate. In: Wikipedia. https://en.wikipedia.org/wiki/Clofibrate
  3. Clofibrate. In: Wikidata. https://www.wikidata.org/wiki/Q2701912
  4. Clofibrate. In: PubChem Compound. CID 2796. https://pubchem.ncbi.nlm.nih.gov/compound/2796